0549 Positive Airway Pressure for Obstructive Sleep Apnea in Systolic Heart Failure Patients Reduces Healthcare Resource Utilization

Abstract Introduction The prevalence of obstructive sleep apnea (OSA) is high in patients with systolic heart failure (HFrEF) and has been associated poor prognosis this patient population. impact positive airway pressure (PAP) therapy OSA HFrEF remains unclear. This retrospective study sought to investigate the association between 1-year adherence PAP healthcare resource utilization (HCRU) newly diagnosed comorbid HFrEF. Methods A national sample administrative claims data linked objective usage was used for analysis. Included either had two encounters or one hospitalization a ICD-10 diagnosis code year prior being initiated on therapy. HCRU measured as composite outcome hospitalizations, emergency room (ER) visits. Propensity score matching create well-balanced groups differing levels assess outcomes. Risk-adjusted models were generate number needed treat (NNT) that referred need become adherent from non-adherent avoid 1 visit. Results We identified 3,182 HFrEF, after propensity matching, 738 remained each group (adherent vs. non-adherent). After therapy, fewer visits than (0.92 1.15 per subject, p = 0.006), which driven by 24% reduction ER patients. Composite visit costs lower versus ($3,500 $5,879, p=0.03). NNT entire cohort 1.5 Conclusion who have hospitalizations not adherent. These results highlight clinical economic benefits treating Support (if any) Funding Source: ResMed